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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
26.97
Human Site:
Y1743
Identified Species:
49.44
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
Y1743
M
K
D
E
Q
V
F
Y
I
Q
Y
L
K
S
M
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
Y1721
K
H
E
D
R
E
I
Y
P
Q
H
L
K
S
L
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
Y1743
M
K
D
E
Q
V
F
Y
I
Q
Y
L
K
S
M
Dog
Lupus familis
XP_534693
2280
250152
Y1813
M
K
D
E
Q
V
F
Y
I
Q
Y
L
K
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
Y1740
M
K
D
E
H
V
F
Y
I
Q
Y
L
K
S
M
Rat
Rattus norvegicus
NP_001101807
1374
149708
H931
R
P
L
P
T
Q
I
H
I
K
S
L
T
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
Y1703
K
H
E
D
R
Q
I
Y
T
Q
H
L
K
S
L
Chicken
Gallus gallus
XP_415317
2195
241321
Y1729
M
K
D
E
Q
V
F
Y
I
Q
H
L
K
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
Y1650
W
S
E
E
R
H
I
Y
A
Q
H
L
K
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
A2157
S
D
E
I
R
C
L
A
L
N
I
F
S
Q
C
Honey Bee
Apis mellifera
XP_393643
1982
216109
N1539
L
K
S
K
D
E
R
N
R
A
P
Y
R
L
Y
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
F2336
A
K
P
I
P
D
Y
F
N
D
A
K
I
P
F
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
D684
T
G
F
G
P
A
A
D
L
D
R
T
I
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
33.3
100
100
N.A.
93.3
13.3
N.A.
33.3
86.6
N.A.
40
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
66.6
100
100
N.A.
93.3
26.6
N.A.
66.6
100
N.A.
66.6
N.A.
20
26.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
8
8
8
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
39
16
8
8
0
8
0
16
0
0
0
0
0
% D
% Glu:
0
0
31
47
0
16
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
39
8
0
0
0
8
0
0
16
% F
% Gly:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
16
0
0
8
8
0
8
0
0
31
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
31
0
47
0
8
0
16
8
0
% I
% Lys:
16
54
0
8
0
0
0
0
0
8
0
8
62
0
0
% K
% Leu:
8
0
8
0
0
0
8
0
16
0
0
70
0
8
31
% L
% Met:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% M
% Asn:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% N
% Pro:
0
8
8
8
16
0
0
0
8
0
8
0
0
8
0
% P
% Gln:
0
0
0
0
31
16
0
0
0
62
0
0
0
8
0
% Q
% Arg:
8
0
0
0
31
0
8
0
8
0
8
0
8
0
0
% R
% Ser:
8
8
8
0
0
0
0
0
0
0
8
0
8
62
0
% S
% Thr:
8
0
0
0
8
0
0
0
8
0
0
8
8
0
8
% T
% Val:
0
0
0
0
0
39
0
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
62
0
0
31
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _